Article
Multigenic control of skin tumor susceptibility in SENCARA/Pt mice.
Carcinogenesis - 1 Jun 1998
Mock B A, Lowry D T, Rehman I, Padlan C, Yuspa S H, Hennings H
Abstract excerpt
Skin tumors induced in mice by initiation-promotion (2 microg DMBA-2 microg TPA) protocols were found to be under multigenic control. Eighty-one N2 mice from the cross (BALB/cAnPt x SENCARA/Pt)F1 x SENCARA/Pt that were either solidly resistant (no papillomas) or highly susceptible (> or = 7 papillomas/mouse) were subjected to a 'genome scan' using 89 microsatellite markers to check for associations with...
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