Multigenic control of skin tumor susceptibility in SENCARA/Pt mice.

doi:10.1093/carcin/19.6.1109

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Article

Multigenic control of skin tumor susceptibility in SENCARA/Pt mice.

Carcinogenesis - 1 Jun 1998

Mock B A, Lowry D T, Rehman I, Padlan C, Yuspa S H, Hennings H

Abstract excerpt

Skin tumors induced in mice by initiation-promotion (2 microg DMBA-2 microg TPA) protocols were found to be under multigenic control. Eighty-one N2 mice from the cross (BALB/cAnPt x SENCARA/Pt)F1 x SENCARA/Pt that were either solidly resistant (no papillomas) or highly susceptible (> or = 7 papil...

Topics

Alleles
Animals
Chromosome Mapping
Crosses, Genetic
Female
Genetic Linkage
Genetic Markers
Genetic Predisposition to Disease
Loss of Heterozygosity
Mice
Microsatellite Repeats
Papilloma
Phenotype
Skin Neoplasms

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