Genetic factors controlling responsiveness to skin tumor promotion in mice.

Abstract excerpt

Two genetic models that could explain all of the current data are depicted in Figure 4, although it should be stressed that proof of any model will require additional genetic analyses. The first model (Model A) indicates that one or more loci controlling responsiveness to TPA are also responsible for directly controlling responsiveness to other classes of skin tumor promoters such as BzPo and Chr. We have called...

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