Article
Microsatellite DNA variants between the inbred SENCAR mouse strains.
Molecular carcinogenesis - 1 Aug 2000
Benavides F, Stern M C, Glasscock E, DiGiovanni J, Coghlan L G, Conti C J
Abstract excerpt
The two-stage model, initiation with 7,12-dimethylbenz[a]anthracene and promotion with 12-O-tetradecanoylphorbol-13-acetate, of mouse skin carcinogenesis has been the protocol of choice to study the genetic susceptibility to carcinogens, the outbred SENCAR mouse being the most widely used skin tumor-sensitive animal model. Squamous cell carcinomas (SCCs) develop from many of the papillomas, making these mice a...
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