Article
Genetic analyses of mouse skin tumor progression susceptibility using SENCAR inbred derived strains.
Molecular carcinogenesis - 1 Sept 2002
Stern Mariana C, Benavides Fernando, LaCava Margaret, Conti Claudio J
Abstract excerpt
Susceptibility to tumor development varies among individuals in the human population. This variability can also be found among different strains of mice, particularly in the mouse skin chemical carcinogenesis model. The genetic mechanisms underlying mouse skin tumor susceptibility are not fully understood. The SENCAR stock has been found to be the most sensitive mice for skin carcinogenesis studies; however,...
Topics
- Animals
- Carcinoma, Squamous Cell
- Chimera
- Chromosome Mapping
- Chromosomes
- Crosses, Genetic
- Disease Progression
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Incidence
- Keratins
- Mice
- Mice, Inbred SENCAR
- Papilloma
- Skin Neoplasms
