Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetics of skin tumor promotion.

Progress in experimental tumor research - 1 Jan 1999

Angel J M, DiGiovanni J

Abstract excerpt

Cancer development is a multistep process that involves both the activation of protooncogenes and the inactivation of tumor suppressor genes. Furthermore, both epidemiological and experimental data indicate that a third class of genes, tumor susceptibility genes, control the propensity to develop carcinogen-induced tumors. Recent studies suggest that tumor susceptibility is determined by the combined effect of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to Genetic Predisposition to Disease
Share to Mice

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mice, Inbred Strains

Share to Skin Neoplasms

Share to Carcinogens

Source

Identifiers

PMID: 10377758
DOI: 10.1159/000062010

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetics of skin tumor promotion.PMID 10377758Read ↗

Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans.Semantic proximity Read ↗

Association of a murine chromosome 9 locus (Psl1) with susceptibility to mouse skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.Semantic proximity Read ↗

Fine mapping reveals that promotion susceptibility locus 1 (Psl1) is a compound locus with multiple genes that modify susceptibility to skin tumor development.Semantic proximity Read ↗

Identification of novel genetic loci contributing to 12-O-tetradecanoylphorbol-13-acetate skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice.Semantic proximity Read ↗

Confirmation of the mapping of a 12-O-tetradecanoylphorbol-13-acetate promotion susceptibility locus, Psl1, to distal mouse chromosome 9.Semantic proximity Read ↗

Genetic factors controlling responsiveness to skin tumor promotion in mice.Semantic proximity Read ↗

New chemically induced skin tumour susceptibility loci identified in a mouse backcross between FVB and dominant resistant PWK.Semantic proximity Read ↗

Proteomic and pathway analyses reveal a network of inflammatory genes associated with differences in skin tumor promotion susceptibility in DBA/2 and C57BL/6 mice.Semantic proximity Read ↗

A subset of skin tumor modifier loci determines survival time of tumor-bearing mice.Semantic proximity Read ↗

Milestones in skin carcinogenesis: the biology of multistage carcinogenesis.Semantic proximity Read ↗

Multigenic control of skin tumor susceptibility in SENCARA/Pt mice.Semantic proximity Read ↗

A wild-derived inbred mouse strain, MSM/Ms, provides insights into novel skin tumor susceptibility genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.