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Article

A novel toxinotyping scheme and correlation of toxinotypes with serogroups of Clostridium difficile isolates.

Journal of clinical microbiology - 1 Aug 1998

Rupnik M, Avesani V, Janc M, von Eichel-Streiber C, Delmée M

Abstract excerpt

Two hundred nineteen Clostridium difficile isolates from 22 serogroups were screened for changes in the genes coding for toxin B (tcdB) and toxin A (tcdA). Parts of the toxin genes were amplified, and the PCR fragments were checked for length polymorphisms and cut with several restriction enzymes to monitor restriction fragment length polymorphisms (RFLPs). For 47 strains (21%), differences in the toxin genes...

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Identifiers

PMID: 9665999
DOI: 10.1128/JCM.36.8.2240-2247.1998
PMCID: PMC105025

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