Article
An Update on Clostridium difficile Toxinotyping.
Journal of clinical microbiology - 1 Jan 2016
Rupnik Maja, Janezic Sandra
Abstract excerpt
Toxinotyping is a PCR-restriction fragment length polymorphism (RFLP)-based method for differentiation of Clostridium difficile strains according to the changes in the pathogenicity locus (PaLoc), a region coding for toxins A and B. Toxinotypes are a heterogenous group of strains that are important in the development of molecular diagnostic tests and vaccines and are a good basis for C. difficile phylogenetic...
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