Article
Genomic and phenotypic studies among Clostridioides difficile isolates show a high prevalence of clade 2 and great diversity in clinical isolates from Mexican adults and children with healthcare-associated diarrhea.
Microbiology spectrum - 2 Jul 2024
Meléndez-Sánchez D, Hernández Laura, Ares Miguel, Méndez Tenorio A, Flores-Luna Lourdes, Torres Javier, Camorlinga-Ponce M
Abstract excerpt
Clostridioides difficile (C. difficile) is widely distributed in the intestinal tract of humans, animals, and in the environment. It is the most common cause of diarrhea associated with the use of antimicrobials in humans and among the most common healthcare-associated infections worldwide. Its pathogenesis is mainly due to the production of toxin A (TcdA), toxin B (TcdB), and a binary toxin (CDT), whose genetic...
Topics
- Humans
- Clostridioides difficile
- Diarrhea
- Mexico
- Child
- Bacterial Toxins
- Adult
- Phylogeny
- Clostridium Infections
- Cross Infection