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Article

Molecular characterization of pathogenicity locus (PaLoc) and tcdC genetic diversity among tcdA+B+Clostridioides difficile clinical isolates in Tehran, Iran.

Anaerobe - 1 Dec 2020

Kodori Mansoor, Ghalavand Zohreh, Yadegar Abbas, Eslami Gita, Azimirad Masoumeh, Krutova Marcela, Abadi Alireza, Zali Mohammad Reza

Abstract excerpt

Clostridioides difficile is the main cause of healthcare-associated diarrhea worldwide. It is proposed that certain C. difficile toxinotypes with distinct pathogenicity locus (PaLoc) variants are associated with disease severity and outcomes. Additionally, few studies have described the common C. difficile toxinotypes, and also little is known about the tcdC variants in Iranian isolates. We characterized the...

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PMID: 33181348
DOI: 10.1016/j.anaerobe.2020.102294

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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