Article
Mice lacking Bmp6 function.
Developmental genetics - 1 Jan 1998
Solloway M J, Dudley A T, Bikoff E K, Lyons K M, Hogan B L, Robertson E J
Abstract excerpt
Bmp6, a member of the 60A subgroup of bone morphogenetic proteins (BMPs), is expressed in diverse sites in the developing mouse embryo from preimplantation stages onwards. To evaluate roles for Bmp6 signaling in vivo, gene targeting was used to generate a null mutation at the Bmp6 locus. The resulting Bmp6 mutant mice are viable and fertile, and show no overt defects in tissues known to express Bmp6 mRNA. The...
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