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Article

Differential p53, p21, mdm2 and Rb regulation in glioma cell lines that overexpress wild-type p53.

International journal of oncology - 1 Aug 1998

Pykett M J, Azzam E, Dahlberg W, Little J B

Abstract excerpt

Gliomas are part of a subset of tumors in which overexpression of p53 protein in the absence of p53 gene mutation has been described. We have utilized a series of glioma cell lines to study the effects of ionizing radiation on the regulation of p53, p21, mdm2 and Rb proteins. The induction of p53 protein in glioma cell lines that overexpress wild-type p53 differs from normal control cells and glioma cell lines...

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Identifiers

PMID: 9664113
DOI: 10.3892/ijo.13.2.213

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Differential p53, p21, mdm2 and Rb regulation in glioma cell lines that overexpress wild-type p53.PMID 9664113Read ↗

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