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Article

Rearranged p53 gene with loss of normal allele in a low-grade nonrecurrent glioma.

Cancer genetics and cytogenetics - 1 Nov 1994

Ghosh M, Dinda A, Chattopadhyay P, Sarkar C, Bhatia S, Sinha S

Abstract excerpt

We are studying the p53 gene profile in primary glial tumors by seeking alterations in the hybridization pattern of the tumor DNA probed with a p53 gene probe. This report documents a rearranged p53 gene with loss of the normal allele in a low-grade mixed glioma which has not recurred during 4-year follow-up. The tumor had a low 5-bromodeoxyuridine (BrdU)-labeling index and low AgNOR count. The p53 protein was...

Topics

Alleles
Brain Neoplasms
Gene Rearrangement
Genes, p53
Glioma
Humans
Male
Middle Aged

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 7987808
DOI: 10.1016/0165-4608(94)90048-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7987808-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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