Article
The effect of retinoic acid on the re-establishment of differentiated hepatocyte phenotype in primary culture.
Cell and tissue research - 1 Aug 1998
Falasca L, Favale A, Serafino A, Ara C, Conti Devirgiliis L
Abstract excerpt
The usefulness of cultured hepatocytes is limited by the gradual loss of their typical physiological functions that occurs in vitro, mainly due to the absence of microenviromental conditions found in vivo. In this study we describe the effect of retinoic acid on the re-establishment of morphological characteristics and on the reorganization of the cytoskeletal network in cultured rat hepatocytes. Results obtained...
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