Article
Maturation of peroxisomes in differentiating human hepatoblastoma cells (HepG2): possible involvement of the peroxisome proliferator-activated receptor alpha (PPAR alpha).
Differentiation; research in biological diversity - 1 Nov 1998
Stier H, Fahimi H D, Van Veldhoven P P, Mannaerts G P, Völkl A, Baumgart E
Abstract excerpt
We have studied the alterations of peroxisomes in the human hepatoblastoma cell line HepG2, induced to differentiate by long-term cultivation (20 days without passaging) using morphological and biochemical techniques as well as mRNA analysis. Ultrastructural studies revealed alterations in shape and size of peroxisomes, with significant increases in mean diameter and formation of small clusters exhibiting...
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