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Article

An internal domain of Exo70p is required for actin-independent localization and mediates assembly of specific exocyst components.

Molecular biology of the cell - 1 Jan 2009

Hutagalung Alex H, Coleman Jeff, Pypaert Marc, Novick Peter J

Abstract excerpt

The exocyst consists of eight rod-shaped subunits that align in a side-by-side manner to tether secretory vesicles to the plasma membrane in preparation for fusion. Two subunits, Sec3p and Exo70p, localize to exocytic sites by an actin-independent pathway, whereas the other six ride on vesicles along actin cables. Here, we demonstrate that three of the four domains of Exo70p are essential for growth. The...

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Source

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Identifiers

PMID: 18946089
DOI: 10.1091/mbc.e08-02-0157
PMCID: PMC2613103

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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