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Article

p53 Protein Is a Suppressor of Papillomavirus DNA Amplificational Replication

1 Aug 1998

Abstract excerpt

p53 protein was able to block human and bovine papillomavirus DNA amplificational replication while not interfering with Epstein-Barr virus oriP once-per-cell cycle replication. Oligomerization, intact DNA-binding, replication protein A-binding, and proline-rich domains of the p53 protein were essential for efficient inhibition, while the N-terminal transcriptional activation and C-terminal regulatory domains...

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Identifiers

PMID: 9658131
DOI: 10.1128/jvi.72.8.6822-6831.1998

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