The sources of variation in the human genome and genome instability in human cancers.

Article

The sources of variation in the human genome and genome instability in human cancers.

Romanian journal of physiology : physiological sciences - 1 Jan 2000

Diculescu G L

Abstract excerpt

The human genome is viewed as a stable collection of about 60,000-70,000 genes--a minority of protein--coding DNA sequences--dispersed in a large majority of noncoding DNA sequences--more than 90 per cent of the entire genome sequences. Some of these ubiquitous noncoding DNA sequences, metonymica...

Topics

Chromosome Aberrations
Chromosome Fragility
DNA Damage
Gene Rearrangement
Genetic Variation
Genome, Human
Humans
Neoplasms

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