Article

Chromosomal Instability in Genome Evolution: From Cancer to Macroevolution

2023-02-07

Abstract excerpt

The integrity of the genome is crucial for the survival of all living organisms. However, genomes need to adapt to survive certain pressures and for this propose use several mechanisms to diversify. Chromosomal instability (CIN) is one of the main mechanism leading to the creation of genomic heterogeneity by altering the number of chromosomes as well as changing their structures. In this review we will discuss the...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1b5efe58-0113-55b8-b346-ca79f26a14cf
DOI: 10.20944/preprints202302.0132.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Chromosomal Instability in Genome Evolution: From Cancer to MacroevolutionDOI 10.20944/preprints202302.0132.v1Read

Causes of genome instability.Semantic proximity Read

Genomic instability and cancer.Semantic proximity Read

Multi-Layered Cancer Chromosomal Instability PhenotypeSemantic proximity Read

Genomic instability: on the birth and death of cancer.Semantic proximity Read

The Cytogenomic “Theory of Everything”: Chromohelkosis May Underlie Chromosomal Instability and Mosaicism in Disease and AgingSemantic proximity Read

Cancer chromosomal instability: therapeutic and diagnostic challengesSemantic proximity Read

Signatures of chromosomal instability in human cancersSemantic proximity Read

The Role of Chromosomal Instability in Cancer and Therapeutic ResponsesSemantic proximity Read

Chromothripsis: how does such a catastrophic event impact human reproduction?Semantic proximity Read

The genomic characteristics and cellular origin of chromothripsis.Semantic proximity Read

Genome chaos: Creating new genomic information essential for cancer macroevolution.Semantic proximity Read

The Spiral Model of Evolution: Stable Life Forms of Organisms and Unstable Life Forms of Cancers.Semantic proximity Read