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Article

Retroviral transduction of TLS-ERG initiates a leukemogenic program in normal human hematopoietic cells

7 Jul 1998

Abstract excerpt

Many chimeric oncogenes have been identified by virtue of the association between chromosomal translocation and specific human leukemias. However, the biological mechanism by which these oncogenes disrupt the developmental program of normal human hematopoietic cells during the initiation of the leukemogenic process is poorly understood due to the absence of an appropriate experimental system to study their...

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PMID: 9653171
DOI: 10.1073/pnas.95.14.8239

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