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Article

Mechanisms of leukemia translocations

6 Jun 2008

Abstract excerpt

PURPOSE OF REVIEW: This review highlights recent findings about the known DNA repair machinery, its impact on chromosomal translocation mechanisms and their relevance to leukemia in the clinic. RECENT FINDINGS: Chromosomal translocations regulate the behavior of leukemia. They not only predict outcome but they define therapy. There is a great deal of knowledge on the products of leukemic translocations, yet...

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PMID: 18536572
DOI: 10.1097/moh.0b013e328302f711

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