Article
Prognostic value of mutations and a germ line polymorphism of the p53 gene in non-small cell lung carcinoma: association with clinicopathological features.
Cancer letters - 5 Jun 1998
Tagawa M, Murata M, Kimura H
Abstract excerpt
The prognostic value of the mutation of the p53 tumor suppressor gene in non-small cell lung carcinomas (NSCLC) is controversial and a polymorphism of the p53 gene at codon 72 consisting of two alleles, arginine (Arg) and proline (Pro), has been reported to be associated with the incidence of smo...
Topics
- Adenocarcinoma
- Aged
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Female
- Genes, p53
- Humans
- Lung Neoplasms
- Male
- Middle Aged
- Mutation
- Polymorphism, Genetic
- Polymorphism, Single-Stranded Conformational
- Prognosis
- Smoking