Article
Prognostic value of mutations and a germ line polymorphism of the p53 gene in non-small cell lung carcinoma: association with clinicopathological features.
Cancer letters - 5 Jun 1998
Tagawa M, Murata M, Kimura H
Abstract excerpt
The prognostic value of the mutation of the p53 tumor suppressor gene in non-small cell lung carcinomas (NSCLC) is controversial and a polymorphism of the p53 gene at codon 72 consisting of two alleles, arginine (Arg) and proline (Pro), has been reported to be associated with the incidence of smoking-related NSCLC. We have studied 67 cases of NSCLC in relation to the mutation of the p53 gene by polymerase chain...
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