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Prognostic impact of p53 Pro72 homozygous genotype in non-small cell lung cancer patients.

Oncology reports - 1 Mar 2008

Boldrini Laura, Gisfredi Silvia, Ursino Silvia, Lucchi Marco, Greco Giordana, Mussi Alfredo, Fontanini Gabriella

Abstract excerpt

Mutations of the p53 gene represent the most common genetic alterations in human cancer. Several reports have focused on p53 polymorphisms as risk factors in lung cancer, in particular at codon 72 of exon 4, encoding either an arginine (Arg72R) or a proline (Pro72P) amino acid. Polymorphisms at codon 72 of the p53 gene were determined using a PCR-RFLP-based method. We analysed the relationship of this...

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PMID: 18288414

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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