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Article

Increased risk of non-small cell lung cancer and frequency of somatic TP53 gene mutations in Pro72 carriers of TP53 Arg72Pro polymorphism.

Lung cancer (Amsterdam, Netherlands) - 1 Apr 2006

Szymanowska Amelia, Jassem Ewa, Dziadziuszko Rafał, Borg Ake, Limon Janusz, Kobierska-Gulida Grazyna, Rzyman Witold, Jassem Jacek

Abstract excerpt

The aim of this study was to assess whether the TP53 Arg72Pro polymorphism is associated with an increased risk of non-small cell lung cancer (NSCLC). Additionally, in NSCLC patients, we investigated a potential association between this polymorphism and somatic TP53 gene mutations in tumour cells. The study group included 240 NSCLC patients who underwent curative pulmonary resection. The control group (576...

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Identifiers

PMID: 16499995
DOI: 10.1016/j.lungcan.2005.12.007

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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