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Article

Expanding allelic diversity of Helicobacter pylori vacA.

Journal of clinical microbiology - 1 Sept 1998

van Doorn L J, Figueiredo C, Sanna R, Pena S, Midolo P, Ng E K, Atherton J C, Blaser M J, Quint W G

Abstract excerpt

The diversity of the gene encoding the vacuolating cytotoxin (vacA) of Helicobacter pylori was analyzed in 98 isolates obtained from different geographic locations. The studies focused on variation in the previously defined s and m regions of vacA, as determined by PCR and direct sequencing. Phylogenetic analysis revealed the existence of four distinct types of s-region alleles: aside from the previously...

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Identifiers

PMID: 9705399
DOI: 10.1128/JCM.36.9.2597-2603.1998
PMCID: PMC105169

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