Article
Expanding allelic diversity of Helicobacter pylori vacA.
Journal of clinical microbiology - 1 Sept 1998
van Doorn L J, Figueiredo C, Sanna R, Pena S, Midolo P, Ng E K, Atherton J C, Blaser M J, Quint W G
Abstract excerpt
The diversity of the gene encoding the vacuolating cytotoxin (vacA) of Helicobacter pylori was analyzed in 98 isolates obtained from different geographic locations. The studies focused on variation in the previously defined s and m regions of vacA, as determined by PCR and direct sequencing. Phyl...
Topics
- Amino Acid Sequence
- Asia
- Australia
- Bacterial Proteins
- Bacterial Toxins
- Costa Rica
- DNA Primers
- Genes, Bacterial
- Genetic Variation
- Genotype
- Geography
- Helicobacter pylori
- Humans
- Molecular Sequence Data
- Netherlands
- New Zealand
- Oligonucleotide Probes
- Phylogeny