Article
Helicobacter pylori vacA genotypes and cagA gene in a series of 383 H. pylori-positive patients.
Zeitschrift fur Gastroenterologie - 1 Jul 2000
Rudi J, Kuck D, Rudy A, Sieg A, Maiwald M, Stremmel W
Abstract excerpt
BACKGROUND: Only 10-15% of all patients infected with Helicobacter pylori develop peptic ulcer disease (PUD) or gastric cancer. Apart from immunological factors in the host, virulence determinants of H. pylori such as the vacuolating cytotoxin (VacA) or the cytotoxin-associated protein A (CagA) might represent a predisposition for the development of PUD. METHODS: We studied antral biopsies of 383 H....
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