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Article

Macroscopic Na+ currents in the "Nonconducting" Shaker potassium channel mutant W434F.

The Journal of general physiology - 1 Jul 1998

Starkus J G, Kuschel L, Rayner M D, Heinemann S H

Abstract excerpt

C-type inactivation in Shaker potassium channels inhibits K+ permeation. The associated structural changes appear to involve the outer region of the pore. Recently, we have shown that C-type inactivation involves a change in the selectivity of the Shaker channel, such that C-type inactivated channels show maintained voltage-sensitive activation and deactivation of Na+ and Li+ currents in K+-free solutions,...

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Identifiers

PMID: 9649585
DOI: 10.1085/jgp.112.1.85
PMCID: PMC2229408

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Macroscopic Na+ currents in the "Nonconducting" Shaker potassium channel mutant W434F.PMID 9649585Read ↗

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Two types of inactivation in Shaker K+ channels: effects of alterations in the carboxy-terminal region.Semantic proximity Read ↗

Shaker IR T449 mutants separate C- from U-type inactivation.Semantic proximity Read ↗

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