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Article

Closed state-coupled C-type inactivation in BK channels.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 2016

Yan Jiusheng, Li Qin, Aldrich Richard W

Abstract excerpt

Ion channels regulate ion flow by opening and closing their pore gates. K(+) channels commonly possess two pore gates, one at the intracellular end for fast channel activation/deactivation and the other at the selectivity filter for slow C-type inactivation/recovery. The large-conductance calcium-activated potassium (BK) channel lacks a classic intracellular bundle-crossing activation gate and normally show no...

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Identifiers

PMID: 27298368
DOI: 10.1073/pnas.1607584113
PMCID: PMC4922147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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