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Article

Gating currents in Shaker K+ channels. Implications for activation and inactivation models.

Biophysical journal - 1 Apr 1992

Perozo E, Papazian D M, Stefani E, Bezanilla F

Abstract excerpt

We have studied ionic and gating currents in mutant and wild-type Shaker K+ channels to investigate the mechanisms of channel activation and the relationship between the voltage sensor of the channel and its inactivation particle. The turn on of the gating current shows a rising phase, indicating that the hypothetical identical activation subunits are not independent. Hyperpolarizing prepulses indicate that most...

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Identifiers

PMID: 1600094
DOI: 10.1016/S0006-3495(92)81802-7
PMCID: PMC1260511

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Gating currents in Shaker K+ channels. Implications for activation and inactivation models.PMID 1600094Read ↗

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Gating charge immobilization in Kv4.2 channels: the basis of closed-state inactivation.Semantic proximity Read ↗

Closing in on the resting state of the Shaker K(+) channel.Semantic proximity Read ↗

Cross talk between activation and slow inactivation gates of Shaker potassium channels.Semantic proximity Read ↗

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Initial steps in the opening of a Shaker potassium channel.Semantic proximity Read ↗

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