Article
Correlation between the substitution rate and rate variation among sites in protein evolution.
Genetics - 1 Jul 1998
Zhang J, Gu X
Abstract excerpt
It is well known that the rate of amino acid substitution varies among different proteins and among different sites of a protein. It is, however, unclear whether the extent of rate variation among sites of a protein and the mean substitution rate of the protein are correlated. We used two approac...
Topics
- Animals
- Enzymes
- Evolution, Molecular
- Genes
- Genetic Variation
- Humans
- Models, Genetic
- Models, Statistical
- Phylogeny
- Probability
- Proteins
- Regression Analysis
- Sequence Analysis
- Time
- Vertebrates