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Article

From complete genomes to measures of substitution rate variability within and between proteins.

Genome research - 1 Jul 2000

Grishin N V, Wolf Y I, Koonin E V

Abstract excerpt

Accumulation of complete genome sequences of diverse organisms creates new possibilities for evolutionary inferences from whole-genome comparisons. In the present study, we analyze the distributions of substitution rates among proteins encoded in 19 complete genomes (the interprotein rate distribution). To estimate these rates, it is necessary to employ another fundamental distribution, that of the substitution...

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Identifiers

PMID: 10899148
DOI: 10.1101/gr.10.7.991
PMCID: PMC310923

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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