Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlates of substitution rate variation in mammalian protein-coding sequences.

BMC evolutionary biology - 19 Feb 2008

Welch John J, Bininda-Emonds Olaf R P, Bromham Lindell

Abstract excerpt

BACKGROUND: Rates of molecular evolution in different lineages can vary widely, and some of this variation might be predictable from aspects of species' biology. Investigating such predictable rate variation can help us to understand the causes of molecular evolution, and could also help to improve molecular dating methods. Here we present a comprehensive study of the life history correlates of substitution rate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to DNA Damage
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Evolution, Molecular

Share to Genes, Mitochondrial

Share to Mammals

Share to Open Reading Frames

Share to Regression Analysis

Source

Open in PubMed Open full text

Identifiers

PMID: 18284663
DOI: 10.1186/1471-2148-8-53
PMCID: PMC2289806

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlates of substitution rate variation in mammalian protein-coding sequences.PMID 18284663Read ↗

Strong variations of mitochondrial mutation rate across mammals--the longevity hypothesis.Semantic proximity Read ↗

Lifespan Predicts Mitochondrial Substitution Rates across Vertebrates, but Methodology Matters.Semantic proximity Read ↗

Time dependency of molecular rate estimates and systematic overestimation of recent divergence times.Semantic proximity Read ↗

Estimating absolute rates of synonymous and nonsynonymous nucleotide substitution in order to characterize natural selection and date species divergences.Semantic proximity Read ↗

Inverse relationship between longevity and evolutionary rate of mitochondrial proteins in mammals and birds.Semantic proximity Read ↗

Exploring the correlations between sequence evolution rate and phenotypic divergence across the Mammalian tree provides insights into adaptive evolution.Semantic proximity Read ↗

Nucleotide substitution rate of mammalian mitochondrial genomes.Semantic proximity Read ↗

Explaining the imperfection of the molecular clock of hominid mitochondria.Semantic proximity Read ↗

Reconstructing the phylogenetic history of long-term effective population size and life-history traits using patterns of amino acid replacement in mitochondrial genomes of mammals and birds.Semantic proximity Read ↗

Variation in the Substitution Rates among the Human Mitochondrial Haplogroup U Sublineages.Semantic proximity Read ↗

Elevated substitution rates estimated from ancient DNA sequences.Semantic proximity Read ↗

The rates of molecular evolution in rodent and primate mitochondrial DNA.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.