Article
Differential expression of cytokine transcripts in human epithelial ovarian carcinoma by solid tumour specimens, peritoneal exudate cells containing tumour, tumour-infiltrating lymphocyte (TIL)-derived T cell lines and established tumour cell lines.
Clinical and experimental immunology - 1 May 1998
Nash M A, Lenzi R, Edwards C L, Kavanagh J J, Kudelka A P, Verschraegen C F, Platsoucas C D, Freedman R S
Abstract excerpt
T cell lines derived in low concentrations of recombinant IL-2 (rIL-2) from TIL of patients with epithelial ovarian carcinoma (EOC) often exhibit specific cytotoxicity against autologous tumour cells. However, the ability of T cells at the tumour site to respond to ovarian carcinoma cells may be...
Topics
- Adenocarcinoma
- Ascitic Fluid
- Carcinoma
- Cystadenocarcinoma, Serous
- Cytokines
- Enzyme-Linked Immunosorbent Assay
- Female
- Humans
- Lymphocytes, Tumor-Infiltrating
- Ovarian Neoplasms
- Phenotype
- Polymerase Chain Reaction
- Surface Properties