Large-scale expansion in interleukin-2 of tumor-infiltrating lymphocytes from patients with ovarian carcinoma for adoptive immunotherapy.

doi:10.1016/0022-1759(94)90084-1

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Article

Large-scale expansion in interleukin-2 of tumor-infiltrating lymphocytes from patients with ovarian carcinoma for adoptive immunotherapy.

Journal of immunological methods - 3 Jan 1994

Freedman R S, Tomasovic B, Templin S, Atkinson E N, Kudelka A, Edwards C L, Platsoucas C D

Abstract excerpt

Tumor infiltrating lymphocytes (TIL) from malignant ascites or solid tumor specimens obtained from patients with ovarian carcinoma were expanded to large numbers in vitro (10(10)-10(11)) by a four-step method using AIM V medium and low concentrations of recombinant interleukin-2 (rIL-2). The expa...

Topics

Antigens, CD
Ascites
Carcinoma
Cell Division
Cells, Cultured
Chromium Radioisotopes
Culture Techniques
Cytotoxicity, Immunologic
Female
Humans
Immunotherapy, Adoptive
Interleukin-2
Lymphocytes, Tumor-Infiltrating
Ovarian Neoplasms
Phenotype
T-Lymphocyte Subsets

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Open in PubMed

Identifiers

PMID: 8308273
DOI: 10.1016/0022-1759(94)90084-1

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ACCS

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8308273-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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