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Article

Incidence of DNA replication errors in patients with multiple primary cancers.

Diseases of the colon and rectum - 1 Jun 1998

Brown S R, Finan P J, Hall N R, Bishop D T

Abstract excerpt

PURPOSE: Multiple primary cancers are a feature of hereditary nonpolyposis colorectal cancer in which defects in DNA repair mechanisms result in accumulation of replication errors within tumor DNA. We assessed replication error incidence in multiple primary cancer patients who may have similar genetic defects. METHODS: DNA was obtained from 69 patients from the Yorkshire region who had developed colorectal cancer...

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Identifiers

PMID: 9645746
DOI: 10.1007/BF02236266

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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