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Article

Colorectal neoplasms detected colonoscopically in at-risk members of colorectal cancer families stratified by the demonstration of DNA microsatellite instability.

Journal of molecular medicine (Berlin, Germany) - 1 Sept 1996

Jass J R, Pokos V, Arnold J L, Cottier D S, Jeevaratnam P, Van de Water N S, Browett P J, Winship I M, Lane M R

Abstract excerpt

This study compared colonoscopic findings in families meeting the Amsterdam criteria (A) for hereditary non-polyposis colorectal cancer (HNPCC) but stratified according to whether the familial cancers showed DNA microsatellite instability. DNA was extracted from paired samples of normal and cancer, and microsatellite instability was analysed at up to six loci. Families were termed replication error positive...

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Identifiers

PMID: 8892060
DOI: 10.1007/BF00204981

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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