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Article

Infrequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers of the esophagus and various other tissues.

Japanese journal of cancer research : Gann - 1 Jun 1995

Shimada M, Horii A, Sasaki S, Yanagisawa A, Kato Y, Yamashita K, Okagawa K, Yamasaki K, Ishiguro S, Inoue M

Abstract excerpt

Patients with esophageal cancer are at high risk of developing other primary tumors, especially squamous cell carcinoma in the head and neck. Heavy smoking and excessive consumption of alcohol are considered to be crucial environmental risk-factors for development of these multiple primary cancers. To investigate whether any genetic background, such as defects in the DNA-mismatch repair system, may influence the...

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Identifiers

PMID: 7622413
DOI: 10.1111/j.1349-7006.1995.tb02427.x
PMCID: PMC5920871

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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