Article
Infrequent replication errors at microsatellite loci in tumors of patients with multiple primary cancers of the esophagus and various other tissues.
Japanese journal of cancer research : Gann - 1 Jun 1995
Shimada M, Horii A, Sasaki S, Yanagisawa A, Kato Y, Yamashita K, Okagawa K, Yamasaki K, Ishiguro S, Inoue M
Abstract excerpt
Patients with esophageal cancer are at high risk of developing other primary tumors, especially squamous cell carcinoma in the head and neck. Heavy smoking and excessive consumption of alcohol are considered to be crucial environmental risk-factors for development of these multiple primary cancer...
Topics
- Adenocarcinoma
- Carcinoma, Squamous Cell
- Colorectal Neoplasms, Hereditary Nonpolyposis
- DNA Repair
- DNA, Neoplasm
- DNA, Satellite
- Esophageal Neoplasms
- Humans
- Hypopharyngeal Neoplasms
- Liver Neoplasms
- Neoplasms, Multiple Primary
- Phenotype
- Rectal Neoplasms