Article
Genetic analysis of familial and multiple malignancies of endometrial cancer.
International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics - 1 Aug 1999
Kobayashi K, Sagae S, Takeda T, Sugimura M, Nishioka Y, Kudo R
Abstract excerpt
The presence of the positive replication errors (RER) phenotype in familial and multiple primary malignancies of endometrial cancer, and its association with a poor prognosis was examined. We analyzed 40 endometrial cancers for RER. Eight endometrial cancers with the RER(+) phenotype at multiple microsatellite loci were detected. The presence of the RER(+) phenotype was higher than in non-familial malignancies....
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