Article
Requirement for p56(lck) tyrosine kinase activation in Th subset differentiation.
International immunology - 1 May 1998
Yamashita M, Hashimoto K, Kimura M, Kubo M, Tada T, Nakayama T
Abstract excerpt
The lymphocyte-specific protein tyrosine kinase p56(lck) (Lck) is well documented with regard to its role in regulating T cell activation and thymocyte development through delivery of signals via the mature alphabeta TCR as well as the pre-TCR. Little is known, however, about the role of Lck in T...
Topics
- Amino Acid Sequence
- Animals
- Antibodies, Monoclonal
- Antibody Formation
- CD4 Antigens
- Cell Differentiation
- Cytokines
- Enzyme Activation
- Gene Expression
- Heterozygote
- Lymphocyte Activation
- Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
- Mice
- Mice, Inbred BALB C
- Mice, Inbred C57BL
- Mice, Transgenic
- Molecular Sequence Data
- Ovalbumin