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Article

The lck paradox: because of inconsistent experimental evidence, the role of the protein tyrosine kinase p56lck in early thymic development remains poorly defined.

Developmental immunology - 1 Jan 1998

Eichmann K

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Share to Alleles
Share to Lymphocyte Activation
Share to Lymphocyte Specific Protein Tyrosine Kinase p56(lck)
Share to Receptors, Antigen, T-Cell

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to T-Lymphocytes

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Identifiers

PMID: 9716902
DOI: 10.1155/1998/25758
PMCID: PMC2276014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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The lck paradox: because of inconsistent experimental evidence, the role of the protein tyrosine kinase p56lck in early thymic development remains poorly defined.PMID 9716902Read ↗

Differential requirement for p56lck in fetal and adult thymopoiesis.Semantic proximity Read ↗

An activated lck transgene promotes thymocyte development in RAG-1 mutant mice.Semantic proximity Read ↗

Requirement for p56lck tyrosine kinase activation in T cell receptor-mediated thymic selection.Semantic proximity Read ↗

Requirement for p56(lck) tyrosine kinase activation in Th subset differentiation.Semantic proximity Read ↗

LCK deficiency in CD8 T cells leads to reduced proliferation and increased effector T-cell formation in miceSemantic proximity Read ↗

T lymphocyte development in p56lck deficient mice: allelic exclusion of the TcR beta locus is incomplete but thymocyte development is not restored by TcR beta or TcR alpha beta transgenes.Semantic proximity Read ↗

Molecular and cellular events in early thymocyte development.Semantic proximity Read ↗

Control of lymphopoiesis by p50csk, a regulatory protein tyrosine kinase.Semantic proximity Read ↗

Protein kinase Cζ: A novel protective neonatal T-cell marker that can be upregulated by allergy prevention strategiesSemantic proximity Read ↗

DYRK1A controls the transition from proliferation to quiescence during lymphoid development by destabilizing Cyclin D3.Semantic proximity Read ↗

Requirement for deoxycytidine kinase in T and B lymphocyte developmentSemantic proximity Read ↗

GKLF in thymus epithelium as a developmentally regulated element of thymocyte-stroma cross-talkSemantic proximity Read ↗

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