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Article

Cyclin-specific START events and the G1-phase specificity of arrest by mating factor in budding yeast.

Molecular & general genetics : MGG - 1 May 1998

Oehlen L J, Jeoung D I, Cross F R

Abstract excerpt

The START cell cycle transition in the budding yeast Saccharomyces cerevisiae is catalyzed by the Cdc28 cyclin-dependent kinase associated with Cln-type cyclins. Since ectopic expression of the B-type cyclin CLB5 can efficiently rescue the inviability that results from CLN depletion, we tested the specificity of the CLN and CLB classes of cyclins for promoting START-associated events. Several aspects of the...

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PMID: 9645424
DOI: 10.1007/s004380050722

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cyclin-specific START events and the G1-phase specificity of arrest by mating factor in budding yeast.PMID 9645424Read ↗

G1 cyclins CLN1 and CLN2 repress the mating factor response pathway at Start in the yeast cell cycle.Semantic proximity Read ↗

Cell cycle arrest caused by CLN gene deficiency in Saccharomyces cerevisiae resembles START-I arrest and is independent of the mating-pheromone signalling pathway.Semantic proximity Read ↗

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.Semantic proximity Read ↗

The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae.Semantic proximity Read ↗

Negative regulation of G1 and G2 by S-phase cyclins of Saccharomyces cerevisiae.Semantic proximity Read ↗

Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2.Semantic proximity Read ↗

The yeast mitotic cyclin Clb2 cannot substitute for S phase cyclins in replication origin firing.Semantic proximity Read ↗

Heat shock-mediated cell cycle blockage and G1 cyclin expression in the yeast Saccharomyces cerevisiae.Semantic proximity Read ↗

Fus3p and Kss1p control G1 arrest in Saccharomyces cerevisiae through a balance of distinct arrest and proliferative functions that operate in parallel with Far1p.Semantic proximity Read ↗

CLB5-dependent activation of late replication origins in S. cerevisiae.Semantic proximity Read ↗

Cdc48p is required for the cell cycle commitment point at Start via degradation of the G1-CDK inhibitor Far1p.Semantic proximity Read ↗

An impaired RNA polymerase II activity in Saccharomyces cerevisiae causes cell-cycle inhibition at START.Semantic proximity Read ↗

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