Article
Identification of a gene necessary for cell cycle arrest by a negative growth factor of yeast: FAR1 is an inhibitor of a G1 cyclin, CLN2.
Cell - 30 Nov 1990
Chang F, Herskowitz I
Abstract excerpt
alpha factor is a negative growth factor and differentiation factor that induces G1 arrest and increases transcription of mating genes in S. cerevisiae a cells. We have identified a gene, FAR1 (for "factor arrest"), which is necessary for cell cycle arrest but not for other responses to alpha fac...
Topics
- Amino Acid Sequence
- Base Sequence
- Cell Cycle
- Chromosome Deletion
- Cloning, Molecular
- Cyclins
- Genes, Fungal
- Genes, Suppressor
- Genotype
- Interphase
- Mating Factor
- Molecular Sequence Data
- Open Reading Frames
- Peptides
- Pheromones
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae