An impaired RNA polymerase II activity in Saccharomyces cerevisiae causes cell-cycle inhibition at START.

Abstract excerpt

Saccharomyces cerevisiae cells harboring the temperature-sensitive mutation rpo21-4, in the gene encoding the largest subunit of RNA polymerase II, were shown to be partially impaired for cell-cycle progress at a permissive temperature, and to become permanently blocked at the cell-cycle regulato...

Topics

• Cell Cycle
• Cyclins
• Mutation
• RNA Polymerase II
• Saccharomyces cerevisiae
• Temperature
• Transcription, Genetic