Article
The role of CDC28 and cyclins during mitosis in the budding yeast S. cerevisiae.
Cell - 5 Apr 1991
Surana U, Robitsch H, Price C, Schuster T, Fitch I, Futcher A B, Nasmyth K
Abstract excerpt
cdc28-1N is a conditional allele that has normal G1 (Start) function but confers a mitotic defect. We have isolated seven genes that in high dosage suppress the growth defect of cdc28-1N cells but not of Start-defective cdc28-4 cells. Three of these (CLB1, CLB2, and CLB4) encode proteins strongly...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- Cloning, Molecular
- Cyclins
- DNA, Fungal
- Gene Expression Regulation, Fungal
- Genes, Fungal
- Genes, Suppressor
- Mitosis
- Molecular Sequence Data
- Mutation
- Phenotype
- Plasmids
- Polymerase Chain Reaction
- Protamine Kinase
- Protein Kinases
- Restriction Mapping