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Article

Heat shock-mediated cell cycle blockage and G1 cyclin expression in the yeast Saccharomyces cerevisiae.

Molecular and cellular biology - 1 Feb 1993

Rowley A, Johnston G C, Butler B, Werner-Washburne M, Singer R A

Abstract excerpt

For cells of the yeast Saccharomyces cerevisiae, heat shock causes a transient inhibition of the cell cycle-regulatory step START. We have determined that this heat-induced START inhibition is accompanied by decreased CLN1 and CLN2 transcript abundance and by possible posttranscriptional changes...

Topics

Cell Cycle
Cyclic AMP
Cyclins
Gene Expression Regulation, Fungal
Hot Temperature
Mutation
Protein Kinases
Saccharomyces cerevisiae
Transcription, Genetic

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 8380888
DOI: 10.1128/mcb.13.2.1034-1041.1993
PMCID: PMC358988

Genes

CLN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8380888-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Heat shock-mediated cell cycle blockage and G1 cyclin expression in the yeast Saccharomyces cerevisiae.PMID 8380888Read ↗

CDC68, a yeast gene that affects regulation of cell proliferation and transcription, encodes a protein with a highly acidic carboxyl terminus.Semantic proximity Read ↗

An impaired RNA polymerase II activity in Saccharomyces cerevisiae causes cell-cycle inhibition at START.Semantic proximity Read ↗

Deregulation of CLN1 and CLN2 in the Saccharomyces cerevisiae whi2 mutant.Semantic proximity Read ↗

Comparison of the Saccharomyces cerevisiae G1 cyclins: Cln3 may be an upstream activator of Cln1, Cln2 and other cyclins.Semantic proximity Read ↗

Cyclin-specific START events and the G1-phase specificity of arrest by mating factor in budding yeast.Semantic proximity Read ↗

Cell cycle arrest caused by CLN gene deficiency in Saccharomyces cerevisiae resembles START-I arrest and is independent of the mating-pheromone signalling pathway.Semantic proximity Read ↗

G1 cyclins CLN1 and CLN2 repress the mating factor response pathway at Start in the yeast cell cycle.Semantic proximity Read ↗

Osmotic stress causes a G1 cell cycle delay and downregulation of Cln3/Cdc28 activity in Saccharomyces cerevisiae.Semantic proximity Read ↗

Heat-induced cell cycle arrest of Saccharomyces cerevisiae: involvement of the RAD6/UBC2 and WSC2 genes in its reversal.Semantic proximity Read ↗

New roles for CDC25 in growth control, galactose regulation and cellular differentiation in Saccharomyces cerevisiae.Semantic proximity Read ↗

A Whi7-anchored loop controls the G1 Cdk-cyclin complex at start.Semantic proximity Read ↗

Saccharomyces cerevisiae genes involved in survival of heat shock.Semantic proximity Read ↗

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