Article
Heat shock-mediated cell cycle blockage and G1 cyclin expression in the yeast Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Feb 1993
Rowley A, Johnston G C, Butler B, Werner-Washburne M, Singer R A
Abstract excerpt
For cells of the yeast Saccharomyces cerevisiae, heat shock causes a transient inhibition of the cell cycle-regulatory step START. We have determined that this heat-induced START inhibition is accompanied by decreased CLN1 and CLN2 transcript abundance and by possible posttranscriptional changes to CLN3 (WHI1/DAF1) cyclin activity. Persistent CLN2 expression from a heterologous promoter or the CLN2-1 or CLN3-1...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
