Article
Beta2-adrenoceptor polymorphisms are in linkage disequilibrium, but are not associated with asthma in an adult population.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Apr 1998
Dewar J C, Wheatley A P, Venn A, Morrison J F, Britton J, Hall I P
Abstract excerpt
OBJECTIVE: To determine the association between the beta2-adrenoceptor polymorphisms at amino acids 16 and 27 and markers of allergic disease and asthma per se in a random adult population, and to determine the degree of linkage disequilibrium existing between polymorphisms at amino acid position...
Topics
- Adolescent
- Adult
- Aged
- Alleles
- Analysis of Variance
- Asthma
- Bronchial Hyperreactivity
- Deoxyribonucleases, Type II Site-Specific
- Female
- Gene Frequency
- Genotype
- Humans
- Hypersensitivity, Immediate
- Immunoglobulin E
- Linkage Disequilibrium
- Male
- Middle Aged
- Mutation
