Article
[Association between the genetic polymorphisms of beta2-adrenergic receptor gene and the asthma susceptibility and clinical phenotypes in a Chinese population].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Feb 2002
Fu Jin, Chen Hong, Hu Liangping, Zhang Huiqin, Ma Yu, Chen Yuzhi
Abstract excerpt
OBJECTIVE: To determine whether genetic polymorphisms of beta2-adrenergic receptor gene affect asthma susceptibility and play a role in disease regulation. METHODS: One hundred and sixty-six unrelated childhood asthma cases and 32 families with 192 samples were studied. The polymorphisms at amino acid positions 16, 27, 164 and nucleic acid residue 523 were genotyped by polymerase chain reaction-restriction...
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