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Article

β2-adrenergic receptor gene polymorphisms in normal and asthmatic individuals in the Eastern Province of Saudi Arabia.

Annals of Saudi medicine - 1 Jan 2000

Al-Rubaish Abdullah

Abstract excerpt

BACKGROUND AND OBJECTIVES: Several polymorphisms of the β2-adrenergic receptor (β2-AR) gene have been identified, including the amino acid substitution from arginine (Arg) to glycine (Gly) at codon 16 and from glutamine (Gln) to glutamic acid (Glu) at codon 27. These substitutions affect receptor function and show significantly more agonist-promoted receptor down-regulation than cells expressing the Arg 16/Gln 27...

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Identifiers

PMID: 22048503
DOI: 10.4103/0256-4947.87094
PMCID: PMC3221129

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