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Article

Duct changes and K-ras mutations in the disease-free pancreas: analysis of type, age relation and spatial distribution.

Virchows Archiv : an international journal of pathology - 1 Nov 1999

Lüttges J, Reinecke-Lüthge A, Möllmann B, Menke M A, Clemens A, Klimpfinger M, Sipos B, Klöppel G

Abstract excerpt

Recent molecular studies have suggested that hyperplastic duct lesions of the pancreas are potential precursors of pancreatic ductal carcinoma. This study examines the type, distribution, age-related incidence and K-ras codon 12 mutation rate of duct lesions in the normal pancreas. Postmortem pancreases from 140 patients were screened for the presence of mucinous cell hypertrophy (MHT), ductal papillary...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 10592048
DOI: 10.1007/s004280050428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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