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Article

p53, Ki-ras, and DNA ploidy in human pancreatic ductal adenocarcinomas.

Laboratory investigation; a journal of technical methods and pathology - 1 Jan 1996

Weyrer K, Feichtinger H, Haun M, Weiss G, Ofner D, Weger A R, Umlauft F, Grünewald K

Abstract excerpt

Ki-ras mutations and DNA aneuploidy are common findings in human pancreatic ductal adenocarcinomas. An altered p53 tumor-suppressor gene has been suggested to cooperate with activated Ki-ras in malignant cellular transformation and could enhance genomic instability. We have investigated a panel of well-documented pancreatic carcinomas with defined ploidy and Ki-ras mutations for the presence and pattern of...

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PMID: 8569192

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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