Article
Analysis of K-ras gene mutation in hyperplastic duct cells of the pancreas without pancreatic disease.
Gastroenterology - 1 Jan 1996
Tada M, Ohashi M, Shiratori Y, Okudaira T, Komatsu Y, Kawabe T, Yoshida H, Machinami R, Kishi K, Omata M
Abstract excerpt
BACKGROUND & AIMS: We and others have previously shown that the mutation of K-ras codon 12 was found in the majority of pancreatic adenocarcinomas. The mutation has also been identified in the pancreatic duct with mucous cell hyperplasia in association with chronic pancreatitis. Ductal hyperplasi...
Topics
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- Female
- Gene Frequency
- Genes, ras
- Humans
- Hyperplasia
- Male
- Middle Aged
- Molecular Sequence Data
- Mutation
- Pancreatic Ducts